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HFD mice were subdivided into vehicle-treated (HFD), carnitine orotate complex (Godex) 500 mg/kg/body weight (B.W.) (HFD+G500), and Godex 2,000 mg/kg/B.W

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The potential covariates included source, carnitine dosage, initial body weight, and age, when the basic model was built up, potential covariates were considered to add into E max or ET 50 , respectively